Aiming at the difficulty and high cost of maintenance and repair of unmanned underwater vehicles, this paper discusses the application of PHM technology in terms of system,sub-system and equipment,and proposes a set of airborne and shore-based prognostics and health management(PHM)system framework structures. The key technology is analyzed,based on which the PHM data flow structure of unmanned underwater vehicle is designed. Using the engineering application of PHM technology as a clue,this paper ends up with proposing an overall integration technical scheme of unmanned underwater vehicle PHM.