Inverted Echo Sounder（IES）is the main information acquisition device in the field of deep-sea acoustic tomography，which emits acoustic signals and inverts the physical properties of ocean areas based on the time of reception. However，due to the inhomogeneity of ocean depths，it is difficult to use the information collected by different devices in a uniform way. In response to the above problems，the data collected by the inverted echo sounder in the Gulf of Mexico is studied，the fitting and denoising of propagation time information are realized combining with the IES data transformation method. In addition，an in-depth study on seasonal bias and reference surface transformation is conducted，and a method to consider seasonal bias is proposed，which removes seasonal bias from the measurement data and transforms the time data to the defined reference surface. The robustness of the data processing method is effectively improved. The method in this paper can be applied to the processing of inverse echosounder data in other sea areas，and can also provide a reference for other similar studies.
