Based on FLUENT fluid CFD software,the resistance characteristics of an unmanned underwater vehicle with fins and rudders have been simulated. The reasonable inlet boundary conditions,outlet boundary conditions and the coupling method of pressure and velocity are selected. Compared with the wind tunnel test,the numerical simulation results show that this method has higher prediction accuracy for the resistance characteristics of the unmanned underwater vehicle and more detailed and intuitive display of the flow field. The research results have a certain reference value for the shape design of unmanned underwater vehicle with fins and rudders.