The structure parameters of the model pump(blade angles of impeller at inlet and at outlet)have been optimized by using the global sensitivity analysis method based on surrogate method. The results show that the performance of water-jet propulsion pump and shaft power are more sensitive to the blade angle of impeller at outlet with the total sensitivity of 95% and 68%. While,the performance of the water-jet propulsion pump and shaft power are less sensitive to the blade angle of impeller at inlet with total sensitivity of 5% and 32%. The optimized blade angles of impeller at inlet and outlet are respectively 0.69° and 3.92°,which satisfies the Pareto optimal solution, with the efficiency of the pump increased by 1.7% and the power density increased by 6%.