At the point of the underwater weapon enteriny into water from the air, under the strong fluid impact, the elasticstructure will bear larger load. First, this paper analyzes the largest load when weapon vertically enters into water in the applicationof the approximate theory, and then makes simulation analysis of water-entry process of air-laid weapon using the LS-DYNA, inclu-ding vertical water-entry and oblique water-entry. The computation results show that simulation analysis can simulate water-entry im-pact process of weapon with high accuracy , and comparing to the approximate theory analysis , simulation has lager application rangein water-entry impact calculation of various head-shaped weapons and simulation analysis of water-entry dynamic changing processof various attitudes.